The Microbe of Cancer
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منابع مشابه
Understanding microbe-induced cancers.
Microbes are important causes of human cancers, and our estimation of their significance continues to grow as cancer biology is better dissected. A classification system is proposed that highlights common and proposed microbe-induced pathways toward oncogenesis, with an emphasis on types of targeted cells and host-microbial interactions. The central principles that underlie oncogenesis induced ...
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One of the properties of human that is possible to be invaded by others is body and life. That is the most valuable properties of human and paying attention and having respects to them has been emphasized. Invasion to body of people based on two aspects of law and punishment can cause responsibility. Providing the condition of penetrating microbes into the bodies is like that. Some of these mic...
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Arsenic is a carcinogenic environmental factor found in food and drinking water around the world. The mechanisms in which arsenic alters homeostasis are not fully understood. Over the past few decades, light has been shed on varying mechanisms in which arsenic induces cancer. Such mechanisms include gut microbe perturbations, genotoxic effects, and epigenetic modification. Gut microbe perturbat...
متن کاملInduction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli
Commensal Escherichia coli has been identified as a major protagonist of microbe-induced colorectal oncogenesis. Its tumour-promoting attribute is linked to the expression of DNA-damaging genotoxins. Using a constitutively invasive variant of non-pathogenic E. coli, we demonstrate that chronic presence of internalized E. coli leads to enhanced oncogenicity in colon cancer cells. Instead of geno...
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immune cells exist with interactive networks that dictate good health and disease, including cancer, both within and beyond the gut1–3. This emerging paradigm linking gut bac teria with extraintestinal cancer builds upon earlier work that tumour microenvironments interact with systemic immune and metabolic networks4, and, more specifically, with microbial– immune networks2,5,6. In this way, gut...
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عنوان ژورنال:
دوره 40 شماره
صفحات -
تاریخ انتشار 2016